Archive puzzle

Doctordle #25

Teen fatigue, sore throat, and swollen nodes

Infectious DiseaseMedium

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Case notes

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Case summary

This archived Doctordle case was published on 2026-04-25. It presents "Teen fatigue, sore throat, and swollen nodes" as a Medium Infectious Disease puzzle. The final answer is Infectious Mononucleosis.

Answer

Infectious Mononucleosis

Source

MedlinePlus

Topic pages verified on 2026-07-11

Information summarized from MedlinePlus.gov. MedlinePlus does not endorse Doctordle.

Six clues

  1. Clue 1

    A 17-year-old has marked fatigue, fever, and sore throat.

  2. Clue 2

    Neck lymph nodes are swollen.

  3. Clue 3

    The spleen is mildly enlarged in this fictional case.

  4. Clue 4

    A contact sport is paused because of the spleen concern.

  5. Clue 5

    The illness is commonly associated with Epstein-Barr virus.

  6. Clue 6

    Its nickname is often just one syllable.

Plain-language explanation

Infectious mononucleosis is often associated with Epstein-Barr virus. Common teaching clues include fatigue, sore throat, fever, swollen lymph nodes, and sometimes spleen enlargement.