Archive puzzle
Doctordle #133
Weakness rising from the legs after an infection
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Case notes
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Case notes
Sourced case summary
Open the full case notes after playing. The text is also rendered in the page HTML so search engines can understand the archived puzzle.
Case summary
This archived Doctordle case was published on 2026-08-11. It presents "Weakness rising from the legs after an infection" as a Hard Neurology puzzle. The final answer is Guillain-Barre Syndrome.
Answer
Guillain-Barre Syndrome
Source
Topic pages verified on 2026-07-11
Information summarized from MedlinePlus.gov. MedlinePlus does not endorse Doctordle.
Six clues
Clue 1
A 36-year-old develops tingling and weakness after a recent respiratory illness.
Clue 2
The weakness begins in the feet and moves upward in this fictional case.
Clue 3
Reflexes are reduced during the neurologic examination.
Clue 4
The immune system is affecting peripheral nerves.
Clue 5
Breathing muscles can become involved in severe cases.
Clue 6
The answer is an acute nerve disorder commonly abbreviated GBS.
Plain-language explanation
Guillain-Barre syndrome is a rare disorder in which the immune system attacks peripheral nerves. Weakness may begin in the legs and spread upward, sometimes affecting breathing.
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