Archive puzzle
Doctordle #134
Muscle weakness that worsens with activity
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Case notes
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Case notes
Sourced case summary
Open the full case notes after playing. The text is also rendered in the page HTML so search engines can understand the archived puzzle.
Case summary
This archived Doctordle case was published on 2026-08-12. It presents "Muscle weakness that worsens with activity" as a Hard Neurology puzzle. The final answer is Myasthenia Gravis.
Answer
Myasthenia Gravis
Source
Topic pages verified on 2026-07-11
Information summarized from MedlinePlus.gov. MedlinePlus does not endorse Doctordle.
Six clues
Clue 1
A 34-year-old notices one eyelid drooping late in the day.
Clue 2
Double vision and chewing fatigue worsen after repeated use.
Clue 3
Rest temporarily improves the weakness in this fictional case.
Clue 4
Sensation remains normal despite the muscle symptoms.
Clue 5
The problem involves communication between nerves and muscles.
Clue 6
The answer is an autoimmune neuromuscular condition often abbreviated MG.
Plain-language explanation
Myasthenia gravis is an autoimmune disorder that disrupts communication between nerves and muscles. Weakness often worsens with activity and improves with rest.
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